Table 1 Liver SAMe and SAH levels regulation by anti-miR-873-5p in BDL and Mdr2-/- mice
From: MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis
GROUP | SAMe (pmol/mg prot) | SAH (pmol/mg prot) | SAMe/SAH (pmol/mg prot) | T-TEST SIGNIFICANCE (SAMe/SAH ratio) |
|---|---|---|---|---|
BDL MICE | ||||
Wt | 109.06 ± 42.36 | 63.22 ± 12.03 | 1.75 ± 0.72 | |
miR-Ctrl BDL | 158.61 ± 34.32 | 41.30 ± 13.93 | 4.00 ± 1.11 | 0.042 a |
Anti-miR-873-5p-BDL | 108.80 ± 38.99 | 58.97 ± 7.57 | 1.86 ± 0.67 | 0.046 b |
Mdr2-/- MICE | ||||
miR-Ctrl | 61.81 ± 4.35 | 2.55 ± 0.41 | 21.12 ± 2.75 | |
Anti-miR-873-5p | 53.03 ± 10.22 | 3.27 ± 06.8 | 16.58 ± 3.19 | 0.034 c |
