Fig. 2: KRT80 expression in colorectal tissues and its value in prognosis | Cell Death & Disease

Fig. 2: KRT80 expression in colorectal tissues and its value in prognosis

From: Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway

Fig. 2

a KRT80 mRNA expression in 40 tumor tissues and paired adjacent normal mucosa by quantitative real-time polymerase chain reaction (qRT-PCR). The logarithmic scale of 2-ΔΔCt was used to measure the fold-change. β-actin as internal reference. b Western blot was performed to check KRT80 protein expression in eight paired colorectal carcinoma (CRC) tissue samples, with GAPDH as loading control. N, normal tissue; T, tumor tissue. c Representative immunohistochemical (IHC) staining of KRT80 in normal colorectal mucosa and cancerous tissues. d, e Kaplan–Meier analysis showed disease-free survival (DFS) and overall survival (OS) of CRC patients with KRT80 expression

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