Fig. 4: Enhanced ARHGAP5 expression correlates with GC progression.
From: SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression
a–f Detection of ARHGAP5 levels in GC and normal tissues using Oncomine database (a), TCGA data set (b), NCBI GEO repository (c, d), and tissue array (e, f). In the results from the Oncomine database, 1 represents Normal Gastric Mucosa (n = 29), 2 denotes Gastric Intestinal Type Adenocarcinoma (n = 65), 3 represents Diffuse Gastric Adenocarcinoma (n = 13), and 4 stands for Gastric Mixed Adenocarcinoma (n = 8). The p-values were obtained from the Oncomine database. g–j Analysis of ARHGAP5 levels in relation to the overall survival of patients with GC. g Tissue array, scale bar: 100 µm for the upper panel, 50 µm for the bottom panel, h TCGA data set, and i, j Kaplan–Meier Plotter database. In the results from Kaplan–Meier Plotter database, overall survival analysis of GC patients with lymph node metastasis was shown in j. The data and p-values were obtained from the Kaplan–Meier Plotter database (235635_at). All data indicate the mean ± SD. ****p < 0.0001
