Fig. 5: TRPC6 knockout attenuates oxidative stress-induced cell apoptosis. | Cell Death & Disease

Fig. 5: TRPC6 knockout attenuates oxidative stress-induced cell apoptosis.

From: Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation

Fig. 5

Primary PTC from WT and TRPC6-/- mice were divided into different groups and treated with H2O2 (0.5 mM) for 12 h. a Representative western blot images and the relative quantification of cleaved caspase-3 (CC3). Data are expressed as mean ± SEM, n = 3; *P < 0.05. b Representative TUNEL staining of PTC in each group. Scale Bar = 50 μm. Bar graph is showing the quantification of TUNEL-positive cells. Data are expressed as mean ± SEM, n = 6; *P < 0.05

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