Fig. 2: Drugs altering EtOH metabolism affect the response of mitochondrial dynamics to chrEtOH only in VL-17A cells. | Cell Death & Disease

Fig. 2: Drugs altering EtOH metabolism affect the response of mitochondrial dynamics to chrEtOH only in VL-17A cells.

From: Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism

Fig. 2

a, b GFP spreading in both EtOH and mock-pretreated HepG2 and VL-17A cells transfected with mtDSRed/mtPA-GFP (reproduced from Fig. 1e, f). c, d similar to a, b except that 5 mM 4-MP has been added to the medium simultaneous with EtOH (c n for 4-MP and EtOH+4-MP is 29 and 28; d n for 4-MP and EtOH+4-MP is 37). e, f similar to a, b except that 10 μM ALDA-1 has been added to the medium simultaneously with EtOH e n for ALDA-1 and EtOH+ALDA-1 is 27 and 28; f n for ALDA-1 and EtOH+ALDA-1 is 37) (n = 4)

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