Fig. 1: MiR-486-5p is remarkably downregulated in CRC and predicts poor prognosis. | Cell Death & Disease

Fig. 1: MiR-486-5p is remarkably downregulated in CRC and predicts poor prognosis.

From: DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways

Fig. 1: MiR-486-5p is remarkably downregulated in CRC and predicts poor prognosis.

a–c TCGA, Starbase 2.0, and GEO databases exhibited miR-486-5p is significantly downregulated in CRC. d miR-486-5p is significantly downregulated in CRC compared to ANTs. e, f Our study and TCGA database revealed that CRC patients with low miR-486-5p expression had lower overall survival rates than patients with high miR-486-5p expression. Data are represented as means ± S.D. from at least three independent experiments. g miR-486-5p is significantly downregulated in CRC cells compared to FHC. *p < 0.05, **p < 0.01, ***p < 0.001

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