Fig. 6: Compound KYZ3 inhibited the growth of human xenograft tumor in vivo.

a The growing curves of mice’s tumor size. b The growing curves of mice’s body weight. c Immunohistochemical staining for Ki-67 in tumor tissues obtained from the control and KYZ3-treated mice. d KYZ3 inhibited the levels of p-STAT3 in tumors ***p < 0.001, **p < 0.01, *p < 0.05