Table 1 Characteristics of lung adenocarcinoma patients with EGFR mutations

From: APE1 stimulates EGFR-TKI resistance by activating Akt signaling through a redox-dependent mechanism in lung adenocarcinoma

Variable

Number of patients

p

APE1 staining

Score 0

Score 1

Score 2

Score 3

 

Gender

    

0.65

 Male

1

7

12

13

 

 Female

1

10

8

9

 

Age

    

0.94

 60>

1

10

11

14

 

 ≤60

1

7

9

8

 

Smoking

    

0.45

 Yes

0

4

8

9

 

 No

2

13

12

13

 

T status

    

0.33

 T1

0

2

0

1

 

 T2

1

9

6

6

 

 T3

1

2

5

3

 

 T4

0

4

9

12

 

N status

    

0.38

 N0

1

0

1

3

 

 N1

0

1

4

2

 

 N2

1

13

12

14

 

 N3

0

3

3

3

 

M status

    

0.89

 M0

0

2

3

2

 

 M1

2

15

17

20

 

Treated TKIs

    

0.23

 Gefitinib

1

8

5

3

 

 Erlotinib

1

9

13

15

 

 Icotinib

0

0

2

4

 
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