Fig. 1: miR-1249 was downregulated in CRC cell lines and tissues.

a Decreased miR-1249 expression was observed in all six CRC cell lines compared with the normal colonial epithelial cell (FHC). b qRT-PCR analysis of miR-1249 in 112 pairs of human CRC tissues and their adjacent normal tissues (ANTs). c–e miR-1249 was adverse correlated with pN stage (c), pM stage (d), and TNM stage (e). f Kaplan–Meier analysis of the correlation between miR-1249 expression levels and overall survival (OS) of 112 patients. ***P < 0.001