Fig. 2: The relationship between miR-200c, PTENP1, and PTEN in EEC cell lines. | Cell Death & Disease

Fig. 2: The relationship between miR-200c, PTENP1, and PTEN in EEC cell lines.

From: Estrogen affects the negative feedback loop of PTENP1-miR200c to inhibit PTEN expression in the development of endometrioid endometrial carcinoma

Fig. 2: The relationship between miR-200c, PTENP1, and PTEN in EEC cell lines.

a PTENP1 was downregulated by transfecting RL-952 cells with miR-200c mimics, when PTEN RNA was not significant changed. b PTENP1 was upregulated in RL-952 cells when miR-200c expression was inhibited, when PTEN RNA was not significantly changed. c PTEN was upregulated and miR-200c was downregulated when PTENP1 expression was increased in RL-952 cells. d PTEN was downregulated and miR-200c was upregulated when PTENP1 expression was inhibited in RL-952 cells. e, f The expression of PTENP1 increased or decreased after PTEN overexpression or interference in RL-952 cells, but there was no significant change in miR-200c expression. g the expression of PTEN protein increased or decreased by transfecting RL-952 cells with miR-200c-inhibitor of miR-200c-mimics

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