Fig. 1: Ultrastructural features of autophagy induced by 6-OHDA in MN9D cells. | Cell Death & Disease

Fig. 1: Ultrastructural features of autophagy induced by 6-OHDA in MN9D cells.

From: Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis

Fig. 1: Ultrastructural features of autophagy induced by 6-OHDA in MN9D cells.The alternative text for this image may have been generated using AI.

a Electron micrographs were taken after treatment with or without 100 μM 6-OHDA for 15 h. N represents nucleus. Scale bar represents 2 μm. b Enlarged images of 6-OHDA-treated cells illustrate typical of autophagic vacuoles (AVs; black arrows) and phagophore (white arrows). Scale bar represents 1 μm. c The number of AVs was quantified from ten randomly selected cells per each group. Bars represent the mean ± standard deviation (7.4 ± 1.4 for untreated control vs. 24 ± 5.5 for 6-OHDA-treated cells). ***P < 0.001

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