Table 2 Univariate and multivariate analysis of different prognostic variables and overall survival (OS) in HCC patients
Variables | n | Univariate analysis | Multivariate analysis model | ||
|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
Sex | 1.369 (0.843–1.695) | 0.869 | |||
Female | 58 | ||||
Male | 92 | ||||
Age (year) | 2.016 (0.860–1.961) | 0.692 | |||
<50 | 82 | ||||
≥50 | 68 | ||||
AFP (ng/mL) | 1.654 (0.598–1.693) | 0.581 | |||
≤20 | 69 | ||||
>20 | 81 | ||||
HBsAg | 2.463 (1.596–2.032) | 0.439 | |||
Positive | 94 | ||||
Negative | 56 | ||||
Liver cirrhosis | 0.961 (0.536–1.934) | 0.506 | |||
Presence | 85 | ||||
Absence | 65 | ||||
TNM stage | 0.933 (0.536–1.964) | 0.783 | |||
I/II | 91 | ||||
III/IV | 59 | ||||
Tumor size (cm) | 1.862 (1.639–2.533) | 0.031 | 0.869 (1.036–2.695) | 0.008 | |
≤5 | 76 | ||||
>5 | 74 | ||||
Multiplicity | 0.969 (0.569–1.965) | 0.736 | |||
Single | 71 | ||||
Multiple (≥2) | 79 | ||||
Intrahepatic metastasis | 0.693 (0.669–1.546) | 0.963 | |||
Presence | 85 | ||||
Absence | 65 | ||||
Vascular invasion | 1.236 (1.893–2.361) | 0.901 | |||
Presence | 74 | ||||
Absence | 76 | ||||
miR-29c-3p expression | 2.369 (1.069–2.465) | 0.002 | 2.023 (1.530–3.039) | 0.015 | |
Low | 95 | ||||
High | 55 | ||||
