Fig. 1: TGF-β1 and IL-1β induce human BECs dysfunction.

a, b The effect of TGF-β1 and IL-1β on BBB function was assessed by measuring the TEER (Rb, barrier resistance) and the permeability of the BECs monolayers to FITC-dextran (A.U., arbitrary unit), both plotted as % of control. Data presented are the mean of triplicate values ± SEM of three independent experiments. Statistical analysis was performed using Student’s t-test where **p < 0.01, ***p < 0.001