Fig. 7: Anti-tumor effect of the αM/MPEG-PCL nanomicelles in vivo.

a Nude mice were inoculated with A375 cells. After 7 days, the mice were randomly assigned to four groups treated, respectively, with the normal saline (NS), the empty MPEG-PCL nanomicelles (MPEG-PCL), the free αM or the αM/MPEG-PCL. Tumor development curve were measured on the indicated days. b The body weight in each treatment group on the indicated days. c The numerical statement of tumor weight in different groups on day 21. d Representative pictures of subcutaneous tumors in each treatment group on day 21. *P < 0.05; **P < 0.01; ***P < 0.001 compared to vehicle (NS group)