Fig. 1: Downregulation of miR-142-3p in the myocardiac tissue of CME pig. | Cell Death & Disease

Fig. 1: Downregulation of miR-142-3p in the myocardiac tissue of CME pig.

From: The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1

Fig. 1: Downregulation of miR-142-3p in the myocardiac tissue of CME pig.

a Echocardiographic analysis of Sham and CME pigs. Left ventricle ejection fraction (LVEF, %), left ventricle fractional shortening (LVFS, %), cardiac output (CO, L/min) and left ventricular end-diastolic diameter (LVEDd, mm) were quantitatively analyzed (n = 10). b Hematoxylin and eosin (H&E) staining of local micro-infracted lesions in the myocardium in the CME group. Arrow indicates microspheres (×400) (n = 10). c Hematoxylin-basic fuchsin-picric acid (HBFP) staining of samples from the Sham, and CME groups. Ischemic myocardium appeared in red. Arrow indicated a micro-infracted lesion (×200) (n = 10). d Relative expression of miR-142-3p was determined by quantitative real-time polymerase chain reaction (qRT-PCR) in the heart (n = 10). e The correlation between miR-142-3p levels and LVEF (%) (n = 10). *P < 0.05

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