Table 3 Cardiac function by echocardiography with miR-142-3p antagomiR

From: The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1

Group

n

LVEF (%)

LVFS (%)

CO (l/min)

LVEDd (mm)

NC antagomiR + Sham

5

70.88 ± 2.81

42.69 ± 6.02

3.47 ± 0.86

3.18 ± 0.45

miR-142-3p antagomiR + Sham

5

67.56 ± 2.87

40.03 ± 5.65

3.32 ± 0.94

3.42 ± 0.52

NC antagomiR + CME

5

47.24 ± 3.47*

25.08 ± 7.24*

2.63 ± 0.77*

5.41 ± 0.59*

miR-142-3p antagomiR + CME

5

36.85 ± 3.96**,***

19.94 ± 6.38**,***

2.27 ± 0.69**,***

6.17 ± 0.64**,***

  1. NC negative control, LVEF left ventricle ejection fraction, CO cardiac output, LVEDd left ventricular end-diastolic diameter, LVFS left ventricle fractional shortening, CME coronary microembolization
  2. *P   < 0.05 NC antagomiR  +  Sham versus NC antagomiR + CME; **P   < 0.05 miR-142-3p antagomiR  +  Sham versus miR-142-3p antagomiR + CME; ***P   < 0.05 NC antagomiR  +  CME versus miR-142-3p antagomiR + CME
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