Fig. 6: Lic regulates physiological JNK-mediated thorax closure.
From: MKK3 modulates JNK-dependent cell migration and invasion
Light micrographs of Drosophila wing discs (a, b) and adult thoraxes (c–j) are shown. The endogenous puc expression pattern in the notum region of wing disc (a) was impeded by knockdown lic (b). Compared with the control thorax (c), loss of Lic-produced a thorax cleft phenotype (d), which was enhanced in heterozygous bsk mutants (f), and restored in heterozygous puc mutants (h), or by overexpression of MKK3 (j), whereas heterozygous mutation in bsk or puc, or expression of MKK3 gave no obvious phenotype (e, g, i, respectively)
