Fig. 6: High LC3 expression associates with HMGB1 and poor outcome after postoperative radiotherapy in locally advanced resected ESCC.

a Correlation of HMGB1 and LC3B protein level in clinical ESCC samples. r, Pearson correlation coefficient. b Representative images of IHC staining of LC3B protein in clinical ESCC samples from patients with/without recurrence. R recurrence; NR non-recurrence. c Statistical analysis of IRS of LC3 protein in clinical ESCC samples, unpaired Mann–Whitney U test. d Kaplan-Meier analyses of RFS for ESCC patients with high-level or low-level tumor expression of LC3, Log-rank test