Table 1 Independent prognostic value of ASPN in CRC

From: Cytoplasmic Asporin promotes cell migration by regulating TGF-β/Smad2/3 pathway and indicates a poor prognosis in colorectal cancer

 

OS

DFS

HR(95%CI)

P value

HR(95%CI)

P value

ASPN

Neg vs. pos

0.444(0.213, 0.926)

0.030

0.426 (0.222, 0.817)

0.010

Age (year)

 

1.070 (1.037, 1.104)

<0.001

1.025 (0.998, 1.053)

0.065

Size (cm)

 

1.930 (1.136, 3.281)

0.015

Variable eliminated

 

T stage

T3 vs T1-2

Variable eliminated

 

3.058 (0.929, 10.066)

0.066

 

T4 vs T1-2

Variable eliminated

 

11.886 (3.097, 45.615)

<0.001

N stage

N1 vs N0

2.814 (1.082, 7.322)

0.034

Variable eliminated

 
 

N2 vs N0

2.931 (1.106, 7.769)

0.031

Variable eliminated

 

M stage

M1 vs M0

Variable eliminated

 

2.810 (1.457, 5.423)

0.002

Overall cox model

  

<0.001

 

<0.001