Fig. 5: miR-1260b-mediated suppression of SOCS6 activated KIT signaling. | Cell Death & Disease

Fig. 5: miR-1260b-mediated suppression of SOCS6 activated KIT signaling.

From: miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

Fig. 5

Expression levels of SOCS6, KIT, p-p38, p-ERK, and ERK were detected by western blot. GAPDH was used as an internal control. 1: Lv-vector, 2: Lv-miR-1260b, 3: si-NC, 4: si-SOCS6 in SPCA1 cell line; 1: Sh-vector, 2: Sh-miR-1260b, 3: NC, 4: SOCS6 in H1299 cell line. The data expressed as the mean ± SD (*P < 0.05; **P < 0.01; ***P < 0.001)

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