Fig. 1: Generation and characterization of 8-week-old NEMOΔhepa/Faslpr mice. | Cell Death & Disease

Fig. 1: Generation and characterization of 8-week-old NEMOΔhepa/Faslpr mice.

From: Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease

Fig. 1

a Macroscopic appearance of livers 8-week-old NEMOf/f, NEMOΔhepa, Faslpr, and NEMOΔhepa/Faslpr. The liver (LW) (b) was calculated and represented. c Representative H&E staining of liver sections of 8-week-old animals. d The liver versus the body weight (LW/BW) ratio was calculated and represented. Arrows indicate infiltration and dotted area points to necrosis. e Serum ALT levels of 8-week-old NEMOf/f, NEMOΔhepa, Faslpr, and NEMOΔhepa/Faslpr mice were determined. Results are expressed as mean ± SEM (n = 50 mice, p < 0.001–0.01)

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