Fig. 6: CXCL5 enhances blood vessel growth in Matrigel plugs in vivo. | Cell Death & Disease

Fig. 6: CXCL5 enhances blood vessel growth in Matrigel plugs in vivo.

From: CXCL5 induces tumor angiogenesis via enhancing the expression of FOXD1 mediated by the AKT/NF-κB pathway in colorectal cancer

Fig. 6

a Representative photographs of the Matrigel plug sections stained with H&E. Number of cells manifest the ability of angiogenesis in different groups. Arrows on the lower columns indicate areas of blood cells. Scale bars, 50 μm (magnification ×200). b Representative photographs of the Matrigel plug sections stained with Masson’s trichrome. Number of cells manifest the ability of angiogenesis in different groups. Arrows on the lower columns indicate areas of blood cells. Scale bars, 50 μm (magnification ×200). c Cells migrating to form microvessels in Matrigel containing rhCXLC5 (10 ng) were more than PBS control. d Hemoglobin content of the rhCXCL5- (10 ng) treated group was significantly great compared with that of the PBS control. Matrigel containing bFGF (100 ng) served as a positive control. Data represent the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001

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