Fig. 4: Sortilin positively regulates GSK-3β/β-catenin/Twist pathway in glioblastoma. | Cell Death & Disease

Fig. 4: Sortilin positively regulates GSK-3β/β-catenin/Twist pathway in glioblastoma.

From: Sortilin promotes glioblastoma invasion and mesenchymal transition through GSK-3β/β-catenin/twist pathway

Fig. 4

a, b Western blotting analysis of the expression levels of sortilin, p-GSK-3β, GSK-3β, β-catenin, and Twist in U87 and A172 cell lines treated with 400 nM AF38469 or transfected with Si-Sor. c–f Representative immunofluorescence images to show the expression change of GSK-3β, p-GSK-3β, β-catenin, and Twist in U87 cells; scale bar = 10 μm. Error bars (SD) represent the data of triplicate samples for each marker, paired two-way Student’s t-test; *p < 0.05, **p < 0.01

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