Table 1 The relationship between NPTX2 protein expression and clinical features in CRC from a tissue microarray

From: NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6

 

NPTX2

P-value

 

Low (n  =  196)

High (n = 196)

 

Age (year)

59.48 ± 8.56

60.64 ± 7.45

0.153

Sex

  Male

105

127

0.258

  Female

81

79

 

Tumor size (cm)

4.67 ± 1.54

7.39 ± 2.16

 <0.001

T stage

  T1

9

2

 

  T2

29

7

 <0.001

  T3

43

51

 

  T4

115

136

 

Lymph node invasion

  Yes

57

124

 < 0.001

  No

139

72

 

Distant metastasis

  Yes

22

59

 < 0.001

  No

174

137

 
  1. In Table 1, as measurement data, like age and tumor size, Students’ t test was used for statistical analysis; as categorical variables or ranked data, Chi - square analysis was applied to statistical analysis
  2. The significance bold value of tumor size is 8.14 x 10−38
  3. The significance bold value of T stage is 0.000145
  4. The significance bold value of lymph node invasion is 1.14 x 10−11
  5. The significance bold value of distance metastasis is 3.92 x 10−6
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