Fig. 9: Numb impact in glioblastoma. | Cell Death & Disease

Fig. 9: Numb impact in glioblastoma.

From: Zika virus infection induces MiR34c expression in glioblastoma stem cells: new perspectives for brain tumor treatments

Fig. 9

a Western blot analysis for the indicated proteins on U87MG cells overexpressing NUMB. b NUMB expression analysis in normal and glioma samples (mixed glioma, oligodendroglioma, astrocytoma, and GBM) of the TCGA data (p < 0.001). c Survival analysis of NUMB high vs. low expressers within the GBM subtype of TCGA or all subtypes (d). Patient data were downloaded from the GlioVis data portal. High and low were defined as cutoff equal to the median, and all Kaplan–Meier plots were analyzed using Log-rank statistics and Wilcox p-values

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