Fig. 1: Elevated lysine-specific demethylase 1 (LSD1) expression levels in patients with hepatitis B virus-associated glomerulonephritis (HBV-GN). | Cell Death & Disease

Fig. 1: Elevated lysine-specific demethylase 1 (LSD1) expression levels in patients with hepatitis B virus-associated glomerulonephritis (HBV-GN).

From: The histone demethylase LSD1 promotes renal inflammation by mediating TLR4 signaling in hepatitis B virus-associated glomerulonephritis

Fig. 1

a Immunofluorescence for HBsAg and E-cadherin in HBV-GN and non-HBV-GN groups. E-cadherin was used as a tubule epithelial marker. b Immunohistochemistry for LSD1 in HBV-GN group and other pathological conditions. a Normal control group, b HBV-negative primary glomerulonephritis (PGN) group, c HBV-positive PGN group, d membranous nephropathy (MN), e mesangial-proliferative glomerulonephritis (MsPGN), f minimal change nephropathy (MCN), g focal segmental glomerulosclerosis (FSGS), and h IgA nephropathy (IgAN). d–h The different pathology types for HBV-GN group. c Mean LSD1 staining intensity in each group. Staining intensity was graded on a scale of 0 (no staining) to 3+ (intense staining). Data are expressed as the mean ± SD. *P < 0.05 versus HBV-GN. n.s. not significant

Back to article page