Fig. 8: The proposed mechanism of lysine-specific demethylase 1 (LSD1) involved in promoting hepatitis B virus (HBV)-induced production of proinflammatory mediators via toll-like receptor 4 (TLR4). | Cell Death & Disease

Fig. 8: The proposed mechanism of lysine-specific demethylase 1 (LSD1) involved in promoting hepatitis B virus (HBV)-induced production of proinflammatory mediators via toll-like receptor 4 (TLR4).

From: The histone demethylase LSD1 promotes renal inflammation by mediating TLR4 signaling in hepatitis B virus-associated glomerulonephritis

Fig. 8

LSD1 promotes HBV-induced production of proinflammatory mediators in vitro by epigenetically upregulating TLR4, thereby contributing to the activation of nuclear factor-κB (NF-κB) and JNK pathways

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