Fig. 7: LINC01048 activated the transcription of YAP1 by interacting with TAF15. | Cell Death & Disease

Fig. 7: LINC01048 activated the transcription of YAP1 by interacting with TAF15.

From: USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1

Fig. 7

a YAP1 and TAF15 were upregulated in CSCC tissues. b The expression correlation between TAF15 and YAP1 in CSCC tissues. c TAF15 was overexpressed or silenced in CSCC cells. d The expression level of YAP1 was examined in response to TAF15 overexpression or knockdown. e ChIP assay demonstrated the affinity of TAF15 to YAP1 promoter. Ago2 was used as a negative control. f The interaction between TAF15 and YAP1 promoter was analyzed by luciferase reporter assays. **p < 0.01 vs. control group

Back to article page