Fig. 2: NPTX2 is determined as a target gene of miR-301b.

a Predicted binding sites of miR-301b at NPTX2–3′UTR. b Comparison of luciferase activity in cells transfected with NPTX2-wt + miR-301b NC, NPTX2-wt + miR-301b mimics, NPTX2-mut + miR-301b NC, or NPTX2-mut + miR-301b mimics. Data are expressed by means ± standard deviation and analyzed by one-way ANOVA from three independent experiments. *p < 0.05, compared with the NPTX-wt + miR-301b NC group