Fig. 7: Overexpression of miR-301b reduces the protein expression of NPTX2 while elevating that of p-NF-κB, TNF-α, IL-Iβ, and COX-2. | Cell Death & Disease

Fig. 7: Overexpression of miR-301b reduces the protein expression of NPTX2 while elevating that of p-NF-κB, TNF-α, IL-Iβ, and COX-2.

From: Overexpression of microRNA-301b accelerates hippocampal microglia activation and cognitive impairment in mice with depressive-like behavior through the NF-κB signaling pathway

Fig. 7

a Quantitation of the relative protein expressions of NPTX2, p-NF-κB, TNF-α, IL-Iβ, and COX-2 in each group. b The gray value of NPTX2, p-NF-κB, TNF-α, IL-Iβ, and COX-2 protein bands detected by western blot analysis in each group. Data are expressed by means ± standard deviation and analyzed by one-way ANOVA from three independent experiments. *p < 0.05, compared with the normal group. #p < 0.05, compared with the depression group

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