Table 1 The top 10 genes associated with mental depression, as identified by DisGeNET

From: Overexpression of microRNA-301b accelerates hippocampal microglia activation and cognitive impairment in mice with depressive-like behavior through the NF-κB signaling pathway

Genes

Gene name

Score

PMIDs

SLC6A4

Solute carrier family 6 member 4

0.36

358

BDNF

Brain-derived neurotrophic factor

0.327

194

HTR1A

5-hydroxytryptamine receptor 1A

0.253

57

HTR2A

5-hydroxytryptamine receptor 2A

0.243

35

COMT

Catechol-O-methyltransferase

0.24

51

MAOA

Monoamine oxidase A

0.234

40

TPH1

Tryptophan hydroxylase 1

0.227

22

TPH2

Tryptophan hydroxylase 2

0.226

31

CRHR1

Corticotropin releasing hormone receptor 1

0.222

29

SLC6A3

Solute carrier family 6 member 3

0.222

17

  1. Score of the reliability of the gene-disease pair, based on the type and number of sources where is reported, and the number of pmids; PMIDs: Total number of PMIDs supporting the association
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