Table 4 The levels of TNF-α, IL-Iβ, and COX-2 in supernatant by ELISA

From: Overexpression of microRNA-301b accelerates hippocampal microglia activation and cognitive impairment in mice with depressive-like behavior through the NF-κB signaling pathway

Groups

TNF-α (pg/mL)

IL-Iβ (pg/mL)

COX-2 (pg/mL)

Control

41.32 ± 2.31

56.33 ± 3.65

11.96 ± 2.58

miR-301b mimic

62.36 ± 6.31*

81.36 ± 6.32*

22.29 ± 2.01*

miR-301b inhibitor

25.48 ± 2.03*

36.32 ± 3.18*

4.21 ± 2.36*

NC

44.12 ± 4.00

53.22 ± 4.12

15.63 ± 2.02

SN50

23.69 ± 2.11*

34.32 ± 3.36*

4.68 ± 2.31*

miR-301b mimic + SN50

42.35 ± 2.15

54.73 ± 3.14

13.26 ± 2.23

  1. Data are expressed by means ± standard deviation and analyzed by one-way ANOVA from three independent experiments
  2. *p < 0.05 compared with the control group
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