Fig. 2: CTBP1 diminishes cell adhesion in PCa cell lines. | Cell Death & Disease

Fig. 2: CTBP1 diminishes cell adhesion in PCa cell lines.

From: CTBP1 depletion on prostate tumors deregulates miRNA/mRNA expression and impairs cancer progression in metabolic syndrome mice

Fig. 2

Cell adhesion assay. Different PCa cell lines, with varying levels of CTBP1 expression were tested. a PC3, 22RV1, LNCaP, C4-2, and DU 145 cell lines transfected with a CTBP1 expression (PC3.CTBP1) or control (PC3.PCDNA3) plasmids. C4-2 cell line was tested only for 60 min. b PC3.shCTBP1 and its respective control PC3.PGIPZ. Top, a representative image of fixed cells stained with CV. Bottom, graphical representation of total amount of attached cells per treatment. c PC3 cells were transfected with a control, CTBP1 and/or ZEB1 expression plasmids. Adhesion was tested only for 60 min. In all cases bars represent the average and SD of a representative experiment. Data were analyzed by one-way ANOVA. *p ≤ 0.05

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