Fig. 4: Silencing miR-155 ameliorates TAB2-induced impaired autophagy in mice with AP. | Cell Death & Disease

Fig. 4: Silencing miR-155 ameliorates TAB2-induced impaired autophagy in mice with AP.

From: Inhibition of miR-155 reduces impaired autophagy and improves prognosis in an experimental pancreatitis mouse model

Fig. 4

a IF staining for TAB2 and beclin-1 in the pancreas (×200; green, TAB2; red, beclin-1). b Autophagic vacuoles were detected in pancreatic tissue samples by TEM (×10,000 and ×50,000; arrow, autophagic vacuole). c IF staining for p62 in the pancreas (×200). d Protein expression and analysis of TAB2, p62 and LC3-I/II by western blotting. The gray values were calculated, and data are presented as the mean ± standard deviation (n = 6 per group, *P < 0.05, **P < 0.01)

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