Fig. 6: 3-MA treatment ameliorates pancreatic damage aggravated by miR-155 upregulation in mice. | Cell Death & Disease

Fig. 6: 3-MA treatment ameliorates pancreatic damage aggravated by miR-155 upregulation in mice.

From: Inhibition of miR-155 reduces impaired autophagy and improves prognosis in an experimental pancreatitis mouse model

Fig. 6

a AP was induced by cerulein as previously described. 3-MA was administered to the AAV-9-miR-155 and untreated groups to treat AP. b H&E staining of the pancreas and lung (×200). c Pancreatic histopathological score (n = 6 per group, **P < 0.01). d Immunohistochemical evaluation of beclin-1 and LC3-I/II expression levels in the pancreas (×200). e Immunohistochemical scores of beclin-1 (n = 6 per group, *P < 0.05). f, g Protein expression and analysis of p62 and beclin-1 by western blotting (n = 6 per group, *P < 0.05)

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