Fig. 6: Administration of nec-1 abrogated the exacerbating effect of TRAF2 knockdown on ischemia-induced cell death following MCAO. | Cell Death & Disease

Fig. 6: Administration of nec-1 abrogated the exacerbating effect of TRAF2 knockdown on ischemia-induced cell death following MCAO.

From: TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis

Fig. 6: Administration of nec-1 abrogated the exacerbating effect of TRAF2 knockdown on ischemia-induced cell death following MCAO.

a Representative images of PI staining in the ipsilateral striatum at 24 h after reperfusion. Scale bar: 50 μm. Sham: sham-operated mice. NC: mice injected with lentivirus expressing NC shRNA. TRAF2 KD: mice injected with lentivirus expressing TRAF2 shRNA. Veh: Vehicle. b Quantification of the amounts of PI+ cells in the ipsilateral striatum (n = 3). N.S.: not significant; *p < 0.05; ***p < 0.001

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