Fig. 1: Expression of BRD4 in cancer patients included in The Cancer Genome Atlas (TCGA) database. | Cell Death & Disease

Fig. 1: Expression of BRD4 in cancer patients included in The Cancer Genome Atlas (TCGA) database.

From: Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells

Fig. 1

a BRD4 expression was higher in cancer tissues (BRCA, COAD, ESCA, HNSC, KICH, LUAD, STAD, READ, SARC, SKCM, BLCA, CESC, KIRC, and UCEC) than in tissues of healthy subjects included in the TCGA database. b BRD4 expression was higher in pan-cancer patients (N = 8031) than in healthy subjects (N = 722) included in the TCGA database. c, d BRD4 expression was higher in estrogen receptor (ER)-negative (c) (N = 179)/progesterone receptor (PR)-negative (d) (N = 255) BRCA patients than in ER-positive (N = 601)/PR-positive (N = 522) BRCA patients. e Expression of BRD4 in different subtypes of BRCA patients. f BRD4 expression was higher in Tumor, Node, Metastasis (TNM) stage III and IV LUAD patients (N = 190) than in TNM stage I and II LUAD patients (N = 79) (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, NS no significance)

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