Fig. 5: Effects of S11 and/or CDDP on tumor growth, body weight, organ index, and biomarkers in an CDDP-resistant xenograft model. | Cell Death & Disease

Fig. 5: Effects of S11 and/or CDDP on tumor growth, body weight, organ index, and biomarkers in an CDDP-resistant xenograft model.

From: Targeting HDAC/OAZ1 axis with a novel inhibitor effectively reverses cisplatin resistance in non-small cell lung cancer

Fig. 5

a Tumor volumes, b body weights, and c organ indexes were measured in NCI-H460/CDDP xenografts treated with S11, CDDP, or the combination of S11 and CDDP. d Ac-H4, H4, and OAZ1 expression levels were measured in NCI-H460/CDDP xenograft tumor tissues. β-actin was used as a loading control. *P < 0.05, **P < 0.01, compared to control

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