Fig. 7: Oridonin mediated protective effects on oxidative injury beyond autophagy via P21.
From: Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy
a, b Real-time PCR analyses of p67phox and Gp91phox (n = 6). c, d DCF fluorescence images and the statistical results (n = 6), which showed intracellular ROS in cardiomyocytes transfected with indicated virus and stimulated with Ang II for 12 h with or without oridonin. 3-MA was added 2 h before incubation with DCFH-DA probe. e Total activity of the antioxidant SOD in cell lysate (n = 6). *P < 0.05 versus PBS. #P < 0.05 versus Ang II. n.s. not significant. §P < 0.05 compared with Ang II or Ang II + Ori
