Fig. 1: Liver damage and systemic inflammation in WT and GsdmD−/− (KO) mice after 6 h hemorrhagic shock with resuscitation (HS/R) or acetaminophen overdose (APAP). | Cell Death & Disease

Fig. 1: Liver damage and systemic inflammation in WT and GsdmD−/− (KO) mice after 6 h hemorrhagic shock with resuscitation (HS/R) or acetaminophen overdose (APAP).

From: Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis

Fig. 1: Liver damage and systemic inflammation in WT and GsdmD−/− (KO) mice after 6 h hemorrhagic shock with resuscitation (HS/R) or acetaminophen overdose (APAP).

a, b Circulating ALT level; c, d circulating IL-6 level; and e, f circulating HMGB1 level in WT and GsdmD−/− mice at 6 h after HS/R or APAP. g, h Circulating ALT level in WT and GsdmD−/− mice at 24 h after HS/R or 12 h after APAP. Each symbol in the graphs represents an individual mouse. N = 3–10 per experimental group. Horizontal bar shows mean. *p < 0.05 between indicated groups; **p < 0.001 between the indicated groups

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