Table 1 Serum levels of cholesterol and triglycerides in wild type and p75NTR-deficient mice

From: Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Serum

Wildtype (wt), n = 7

Heterozygous, n = 6

Homozygous (KO), n = 11

Difference KO vs. wt, p-value

Cholesterol (mmol/l)

3.77 ± 0.84

3.50 ± 0.53

2.91 ± 0.48

p = 0.026

Triglyceride (mmol/l)

1.82 ± 0.44

1.51 ± 0.44,50

1.30 ± 0.36

p = 0.044

  1. Serum lipid levels were determined as described in Materials and methods. Statistical analysis was done using one-way ANOVA and Bonferroni post hoc test, and using the SPSS program. P values <0.05 were considered statistically significant