Fig. 4: Functional rebuilding of neuronal circuitry by transplanted hADSCs in SCI mice as revealed by retrograde tracing marker WGA. | Cell Death & Disease

Fig. 4: Functional rebuilding of neuronal circuitry by transplanted hADSCs in SCI mice as revealed by retrograde tracing marker WGA.

From: Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury

Fig. 4

The data show the immunostaining with WGA and NeuN antibodies in the spinal cord slices from various groups. a The negative PBS control group; b the hADSCs transplanted group; c the Sham group; in each group, double staining of WGA and NeuN are performed and representative images from central, rostral, and caudal part around the injured site are shown, demonstrating the morphological and functional integration of hADSC-MN into the host spinal cord tissue; d statistics of the WGA-, NeuN-, and DAPI-positive ratio from each site for various groups of mice (n = 5), Scale bar: 100 μm

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