Fig. 3: MBNL2 is upregulated in breast cancer and lung cancer. | Cell Death & Disease

Fig. 3: MBNL2 is upregulated in breast cancer and lung cancer.

From: The natural compound neobractatin inhibits tumor metastasis by upregulating the RNA-binding-protein MBNL2

Fig. 3

a MDA-MB-231 and A549 cells treated with NBT (2.5 μM) for 4 h and 8 h analyzed by real-time RT-PCR. b MDA-MB-231 and A549 cells treated with 2.5 μM NBT for different times analyzed by western blotting. c Scatter diagram derived from gene expression data in TCGA comparing the expression of MBNL2 in tumor tissue and normal tissue in breast and lung cancers. d MBNL2 expression detected by western blot analysis in Human Umbilical Vein Endothelial Cells (HUVEC), breast cancer MDA-MB-231 and MCF-7 cell lines, and lung cancer A549, H2228, and H1650 cells, with β-actin used as a loading control. e Statistical analysis from western blotting. The data are expressed as the mean ± SD of at least three independent experiments.*P < 0.05, **P < 0.01, ***P < 0.001

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