Fig. 3: RNA-Seq analysis uncovers a high overlapping of misregulated genes upon NIPBL and BRD4 depletion. | Cell Death & Disease

Fig. 3: RNA-Seq analysis uncovers a high overlapping of misregulated genes upon NIPBL and BRD4 depletion.

From: The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes

Fig. 3

a Venn diagrams representing overlapping of misregulated genes upon knocking down of the indicated genes. Numbers on the diagrams indicate the total number of misregulated genes in each condition. Enrichment (enrich.) with the associated p-value between brackets, as determined by hypergeometric test, is also indicated for the different comparisons. b Pearson correlation of altered gene expression after Nipbl knockdown, compared with Brd4 and Brd2 knockdowns. FC fold change. c Gene ontology (GO) analysis of commonly downregulated genes upon NIPBL and BRD4 depletion, showing different categories of biological processes. n indicates the number of genes in the different categories

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