Fig. 3: miRNA expression changes during exposure to HIV viral proteins in macrophages are reflected in lungs of HIV transgenic rats. | Cell Death & Disease

Fig. 3: miRNA expression changes during exposure to HIV viral proteins in macrophages are reflected in lungs of HIV transgenic rats.

From: Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling

Fig. 3

AM were isolated from HIV transgenic and wild-type rats; expression levels of microRNAs were measured by qRT-PCR, normalized to U6. a miR-155; b miR-23a; c miR-27a; d miR-21 (n = 4 per group). *p < 0.05. Student’s test. Exosomes were isolated from BAL fluid of HIV transgenic or wild-type rats; exosomal miRNAs were isolated and detected by qRT-PCR, normalized to U6 snRNA (n = 4 per group). e miR-155; f miR-23a; g miR-27a; h miR-21. *p < 0.05. Student’s test

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