Fig. 6: ERα decreases BCa metastasis by altering circ_0023642 expression in vivo.
From: ERα-mediated alterations in circ_0023642 and miR-490-5p signaling suppress bladder cancer invasion
a IVIS imaging was used to detect tumor growth and metastasis. Representative IVIS images of the four groups of mice show the outcomes observed at 8 weeks after orthotopic implantation of BCa cells into the bladder wall of female nude mice. b Incidence of metastases in different groups of mice at 8 weeks after BCa cell implantation. c Comparison of the number of metastatic foci in the different mouse groups. d Representative images of IHC staining for ERα and EGFR in orthotopic bladder tumor tissues from the four groups
