Table 1 IC50 values for SBI and VPS34-IN1 in BRAFV600E parental and resistant cells

From: Effect of early-stage autophagy inhibition in BRAFV600E autophagy-dependent brain tumor cells

Cell lines

  

SBIuM

VPS34-IN1uM

MAF794 P

3.59

1.98

MAF794 R

3.85

2.30

AM38 P

37.13

1.62

AM38 R

27.91

2.13

  1. Values were calculated for inhibition of growth of BRAFV600E cell lines by using GraphPad Prism Software 7.04 (GraphPad Software Inc.) from dose–response studies (Fig. 1)