Fig. 7: Effects of p38 MAPK pathway inhibitor SB239063 in dynasore induced anti-OS in vivo. | Cell Death & Disease

Fig. 7: Effects of p38 MAPK pathway inhibitor SB239063 in dynasore induced anti-OS in vivo.

From: Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma

Fig. 7

a The representative mouse and tumors of the xenograft mouse modes in DMSO, SB239063 (10 mg/kg), dynasore (10 mg/kg) and combination-treated groups. b Tumor volumes were measured every day since day 3 after model establishment (day 0), and drugs administration were initiated at day 4 (red arrow). c Tumor samples of four xenograft mice groups were under H&E staining (Scare bar: 40 μm). d, e Xenograft tumor tissues were subjected to IHC staining by using Ki67 antibody (Scare bar: 40 μm). *p < 0.05 and **p < 0.01 vs. DMSO group

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