Table 2 Univariate analysis of clinicopathological factors for OS in 153 CRC patients
Characteristics | OS | |
|---|---|---|
Exp(B) (95% CI) | P | |
Age: >60 vs. ≤60 | 0.876 (0.543–1.411) | 0.585 |
Gender: female vs. male | 0.931 (0.590–1.469) | 0.758 |
Tumor location: rectum vs. colon | 1.110 (0.702–1.756) | 0.656 |
Tumor size > 5 cm vs. ≤5 cm | 1.024 (0.642–1.633) | 0.920 |
Gross appearance: exophytic vs. ulcerative | 0.689 (0.396–1.199) | 0.188 |
Histological type: mucinous adenocarcinoma vs. adenocarcinoma | 1.291 (0.662–2.517) | 0.453 |
Tumor differentiation: poor and others vs. well, moderate | 1.556 (0.944–2.563) | 0.083 |
Vascular invasion: positive vs. negative | 1.908 (1.046–3.478) | 0.035 |
T: T3,4 vs. T1,2 | 1.873 (1.046–3.354) | 0.035 |
Lymph node metastasis: positive vs. negative | 2.953 (1.715–5.083) | <0.001 |
M: M1 vs. M0 | 4.450 (2.100–9.431) | <0.001 |
CEA: >5 ng/ml vs. ≤5 ng/ml | 1.694 (1.074–2.672) | 0.024 |
p-STAT3: positive vs. negative | 1.324 (0.837–2.095) | 0.230 |
S1PR1 and p-STAT3: co-expression vs. not co-expression | 2.085 (1.300–3.343) | 0.002 |
