Fig. 1: miR-4521 expression levels in MB patient tissue and MB cell lines.
From: High impact of miRNA-4521 on FOXM1 expression in medulloblastoma
a Total RNA was isolated from MB patient tissue samples (n = 22). A qPCR was performed for miR-4521. A cerebellum medley (pool of 3) was used as a control. b The different patients were grouped according to their molecular subgroup. c A qPCR was performed for miR-4521 and RNU6B in different MB cell lines. Primary astrocytes were used as a control. d Box plot of MB cell lines compared to primary astrocytes. All qPCR data were normalized to RNU6B levels. e Methylation Array of MB patients—in detail, the results for chromosome 17 of representative patients. All experiments were performed in triplicates. Asterisks indicate significance (Mann–Whitney test; *P < 0.05, ***P < 0.001), error bars indicate mean ± S.D
